VNN1 Antikörper (AA 300-415)

Produktnummer ABIN1683272

Der Kaninchen Polyklonal Anti-VNN1-Antikörper wurde für WB und IF validiert. Er ist geeignet, VNN1 in Proben von Human zu detektieren.

Kurzübersicht für VNN1 Antikörper (AA 300-415) (ABIN1683272)

Target: VNN1 (Vanin 1 (VNN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VNN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-VNN1 Antikörper

Bindungsspezifität: AA 300-415

Sequenz: LLSQLDSHPS HSAVVNWTSY ASSIEALSSG NKEFKGTVFF DEFTFVKLTG VAGNYTVCQK DLCCHLSYKM SENIPNEVYA LGAFDGLHTV EGRYYLQICT LLKCKTTNLN TCGDSA

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-415 of human VNN1 (NP_004657.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu VNN1

Target: VNN1 (Vanin 1 (VNN1))

Andere Bezeichnung: VNN1

Hintergrund: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.,VNN1,HDLCQ8,Tiff66,vanin 1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Blood,Blood Pressure regulation,VNN1

Molekulargewicht: 57 kDa

Gen-ID: 8876

UniProt: O95497

Pathways: Negative Regulation of intrinsic apoptotic Signaling