TPSAB1 Antikörper (AA 19-210)

Produktnummer ABIN1683115

Dieses Anti-TPSAB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TPSAB1 in WB. Geeignet für Human.

Kurzübersicht für TPSAB1 Antikörper (AA 19-210) (ABIN1683115)

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPSAB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TPSAB1 Antikörper

Bindungsspezifität: AA 19-210

Sequenz: APAPGQALQR VGIVGGQEAP RSKWPWQVSL RVHGPYWMHF CGGSLIHPQW VLTAAHCVGP DVKDLAALRV QLREQHLYYQ DQLLPVSRII VHPQFYTAQI GADIALLELE EPVNVSSHVH TVTLPPASET FPPGMPCWVT GWGDVDNDER LPPPFPLKQV KVPIMENHIC DAKYHLGAYT GDDVRIVRDD ML

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-210 of human TPSAB1 (NP_003285.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TPSAB1

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Andere Bezeichnung: TPSAB1

Hintergrund: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.,TPSAB1,TPS1,TPS2,TPSB1,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,TPSAB1

Molekulargewicht: 29 kDa/30 kDa

Gen-ID: 7177

UniProt: Q15661