TGFB2 Antikörper (AA 20-160)

Produktnummer ABIN1683015

Dieses Anti-TGFB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TGFB2 in WB. Geeignet für Human.

Kurzübersicht für TGFB2 Antikörper (AA 20-160) (ABIN1683015)

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TGFB2 Antikörper

Bindungsspezifität: AA 20-160

Sequenz: SLSTCSTLDM DQFMRKRIEA IRGQILSKLK LTSPPEDYPE PEEVPPEVIS IYNSTRDLLQ EKASRRAAAC ERERSDEEYY AKEVYKIDMP PFFPSETVCP VVTTPSGSVG SLCSRQSQVL CGYLDAIPPT FYRPYFRIVR F

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-160 of human TGFB2 (NP_001129071.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Andere Bezeichnung: TGFB2

Hintergrund: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.,TGFB2,G-TSF,LDS4,TGF-beta2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Stem Cells,Cardiovascular,Angiogenesis,Angiogenic growth factors,Ligand,TGFB2

Molekulargewicht: 47 kDa/50 kDa

Gen-ID: 7042

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus