T-Bet Antikörper (AA 326-535)
Kurzübersicht für T-Bet Antikörper (AA 326-535) (ABIN1682974)
Target
Alle T-Bet Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 326-535
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Sequenz
- ENFESMYTSV DTSIPSPPGP NCQFLGGDHY SPLLPNQYPV PSRFYPDLPG QAKDVVPQAY WLGAPRDHSY EAEFRAVSMK PAFLPSAPGP TMSYYRGQEV LAPGAGWPVA PQYPPKMGPA SWFRPMRTLP MEPGPGGSEG RGPEDQGPPL VWTEIAPIRP ESSDSGLGEG DSKRRRVSPY PSSGDSSSPA GAPSPFDKEA EGQFYNYFPN
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human TBX21 (NP_037483.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- T-Bet
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Andere Bezeichnung
- TBX21
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Hintergrund
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.,TBX21,T-PET,T-bet,TBET,TBLYM,T-box 21,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Stem Cells,Hematopoietic Progenitors,TBX21
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Molekulargewicht
- 58 kDa
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Gen-ID
- 30009
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UniProt
- Q9UL17
Target
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