LONP1 Antikörper (AA 120-400)

Produktnummer ABIN1680707

Der Kaninchen Polyklonal Anti-LONP1-Antikörper wurde für WB, IHC, IF und IP validiert. Er ist geeignet, LONP1 in Proben von Human zu detektieren.

Kurzübersicht für LONP1 Antikörper (AA 120-400) (ABIN1680707)

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LONP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-LONP1 Antikörper

Bindungsspezifität: AA 120-400

Sequenz: VFPHLPLIAI TRNPVFPRFI KIIEVKNKKL VELLRRKVRL AQPYVGVFLK RDDSNESDVV ESLDEIYHTG TFAQIHEMQD LGDKLRMIVM GHRRVHISRQ LEVEPEEPEA ENKHKPRRKS KRGKKEAEDE LSARHPAELA MEPTPELPAE VLMVEVENVV HEDFQVTEEV KALTAEIVKT IRDIIALNPL YRESVLQMMQ AGQRVVDNPI YLSDMGAALT GAESHELQDV LEETNIPKRL YKALSLLKKE FELSKLQQRL GREVEEKIKQ THRKYLLQEQ L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human LONP1 (NP_004784.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Andere Bezeichnung: LONP1

Hintergrund: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.,LONP1,CODASS,LON,LONP,LonHS,PIM1,PRSS15,hLON,Epigenetics & Nuclear Signaling,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Nucleotide metabolism,LONP1

Molekulargewicht: 85 kDa/100 kDa/106 kDa

Gen-ID: 9361

UniProt: P36776