KAT2B
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB14386
unconjugated
Applikationshinweise
WB,1:500 - 1:2000,IF,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
KAT2B
(K(lysine) Acetyltransferase 2B (KAT2B))
Andere Bezeichnung
KAT2B
Hintergrund
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.,KAT2B,CAF,P/CAF,PCAF,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G2/M DNA Damage Checkpoint,Notch Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,KAT2B