IVNS1ABP Antikörper (AA 1-300)
Kurzübersicht für IVNS1ABP Antikörper (AA 1-300) (ABIN1680538)
Target
Alle IVNS1ABP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 1-300
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                                            Sequenz
- MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEI FNSDSDPHGI SHVKFDDLNP EAVEVLLNYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV CGDYLLSRMD VTSCISYRNF ASCMGDSRLL NKVDAYIQEH LLQISEEEEF LKLPRLKLEV MLEDNVCLPS NGKLYTKVIN WVQRSIWENG DSLEELMEEV QTLYYSADHK LLDGNLLDGQ AEVFGSDDDH IQFVQKKPPR ENGHKQISSS STGCLSSPNA TVQSPKHEWK IVASEKTSNN
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                                            Kreuzreaktivität
- Human, Maus, Ratte
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                                            Produktmerkmale
- Polyclonal Antibodies
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                                            Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- WB,1:500 - 1:2000
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))
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                                            Andere Bezeichnung
- IVNS1ABP
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                                            Substanzklasse
- Influenza Protein
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                                            Hintergrund
- Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity. Protects cells from cell death induced by actin destabilization (By similarity. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20 E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro.,IVNS1ABP,FLARA3,HSPC068,KLHL39,ND1,NS-1,NS1-BP,NS1BP,IVNS1ABP
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                                            Molekulargewicht
- 71 kDa
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                                            Gen-ID
- 10625
- 
                                            UniProt
- Q9Y6Y0
- 
                                            Pathways
- Negative Regulation of intrinsic apoptotic Signaling
 Target
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