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IVNS1ABP Antikörper (AA 1-300)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IVNS1ABP in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1680538

Kurzübersicht für IVNS1ABP Antikörper (AA 1-300) (ABIN1680538)

Target

Alle IVNS1ABP Antikörper anzeigen
IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reaktivität

  • 14
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 14
  • 1
Kaninchen

Klonalität

  • 14
  • 1
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
Dieser IVNS1ABP Antikörper ist unkonjugiert

Applikation

  • 11
  • 8
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-300

    Sequenz

    MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEI FNSDSDPHGI SHVKFDDLNP EAVEVLLNYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV CGDYLLSRMD VTSCISYRNF ASCMGDSRLL NKVDAYIQEH LLQISEEEEF LKLPRLKLEV MLEDNVCLPS NGKLYTKVIN WVQRSIWENG DSLEELMEEV QTLYYSADHK LLDGNLLDGQ AEVFGSDDDH IQFVQKKPPR ENGHKQISSS STGCLSSPNA TVQSPKHEWK IVASEKTSNN

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

    Andere Bezeichnung

    IVNS1ABP

    Substanzklasse

    Influenza Protein

    Hintergrund

    Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity. Protects cells from cell death induced by actin destabilization (By similarity. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20 E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro.,IVNS1ABP,FLARA3,HSPC068,KLHL39,ND1,NS-1,NS1-BP,NS1BP,IVNS1ABP

    Molekulargewicht

    71 kDa

    Gen-ID

    10625

    UniProt

    Q9Y6Y0

    Pathways

    Negative Regulation of intrinsic apoptotic Signaling
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