FLNB Antikörper (AA 1686-1785)

Produktnummer ABIN1679857

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FLNB in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FLNB Antikörper (AA 1686-1785) (ABIN1679857)

Target: FLNB (Filamin B, beta (FLNB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLNB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-FLNB Antikörper

Bindungsspezifität: AA 1686-1785

Sequenz: PDGTEAEADV IENEDGTYDI FYTAAKPGTY VIYVRFGGVD IPNSPFTVMA TDGEVTAVEE APVNACPPGF RPWVTEEAYV PVSDMNGLGF KPFDLVIPFA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1686-1785 of human FLNB (NP_001157789.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:20 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FLNB

Target: FLNB (Filamin B, beta (FLNB))

Andere Bezeichnung: FLNB

Hintergrund: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.,FLNB,ABP-278,ABP-280,AOI,FH1,FLN-B,FLN1L,LRS1,SCT,TABP,TAP,filamin-B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,FLNB

Molekulargewicht: 230-281 kDa

Gen-ID: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location