FKBP5 Antikörper (AA 308-457)
Kurzübersicht für FKBP5 Antikörper (AA 308-457) (ABIN1679852)
Target
Alle FKBP5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 308-457
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Sequenz
- ESKASESFLL AAFLNLAMCY LKLREYTKAV ECCDKALGLD SANEKGLYRR GEAQLLMNEF ESAKGDFEKV LEVNPQNKAA RLQISMCQKK AKEHNERDRR IYANMFKKFA EQDAKEEANK AMGKKTSEGV TNEKGTDSQA MEEEKPEGHV
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 308-457 of human FKBP51/FKBP51/FKBP51/FKBP5 (NP_001139247.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- FKBP5 (FK506 Binding Protein 5 (FKBP5))
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Andere Bezeichnung
- FKBP5
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Hintergrund
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.,FKBP5,AIG6,FKBP51,FKBP54,P54,PPIase,Ptg-10,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,FKBP5
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Molekulargewicht
- 30 kDa/51 kDa
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Gen-ID
- 2289
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UniProt
- Q13451
Target
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