DRG1 Antikörper (AA 158-367)

Produktnummer ABIN1679602

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DRG1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DRG1 Antikörper (AA 158-367) (ABIN1679602)

Target: DRG1 (Developmentally Regulated GTP Binding Protein 1 (DRG1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DRG1 Antikörper

Bindungsspezifität: AA 158-367

Sequenz: KKIIENELEG FGIRLNSKPP NIGFKKKDKG GINLTATCPQ SELDAETVKS ILAEYKIHNA DVTLRSDATA DDLIDVVEGN RVYIPCIYVL NKIDQISIEE LDIIYKVPHC VPISAHHRWN FDDLLEKIWD YLKLVRIYTK PKGQLPDYTS PVVLPYSRTT VEDFCMKIHK NLIKEFKYAL VWGLSVKHNP QKVGKDHTLE DEDVIQIVKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 158-367 of human DRG1 (NP_004138.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DRG1

Target: DRG1 (Developmentally Regulated GTP Binding Protein 1 (DRG1))

Andere Bezeichnung: DRG1

Hintergrund: Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.,DRG1,NEDD3,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,DRG1

Molekulargewicht: 40 kDa

Gen-ID: 4733

UniProt: Q9Y295