CTBP2 Antikörper (C-Term)

Produktnummer ABIN1679396

Der Kaninchen Polyklonal Anti-CTBP2-Antikörper wurde für WB und IF validiert. Er ist geeignet, CTBP2 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für CTBP2 Antikörper (C-Term) (ABIN1679396)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CTBP2 Antikörper

Bindungsspezifität: C-Term

Sequenz: SEPFSFAQGP LKDAPNLICT PHTAWYSEQA SLEMREAAAT EIRRAITGRI PESLRNCVNK EFFVTSAPWS VIDQQAIHPE LNGATYRYPP GIVGVAPGGL PAAMEGIIPG GIPVTHNLPT VAHPSQAPSP NQPTKHGDNR EHPNEQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human CTBP2 (NP_001320.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-CTBP2 Antikörper (ABIN1679396)

Li, Liu, He, Yang, Pei, Li, Liu, Chen, Xie, Xu, Ting, Zhang, Jin, Liu, Zhang, Yuan, Yang, Wu, Zhang, Yang, Yi, Liang, Shang, Sun: "ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin." in: Nature communications, Vol. 8, Issue 1, pp. 691, (2018) (PubMed).

Details zu CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Andere Bezeichnung: CTBP2

Hintergrund: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.,CTBP2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Notch Signaling Pathway,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,CTBP2

Molekulargewicht: 48 kDa/56 kDa/106 kDa

Gen-ID: 1488

UniProt: P56545