HRPT2 Antikörper (AA 435-505)
Kurzübersicht für HRPT2 Antikörper (AA 435-505) (ABIN1679121)
Target
Alle HRPT2 (CDC73) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 435-505
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 435-505 of human CDC73 (Q6P1J9).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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Andere Bezeichnung
- CDC73
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Hintergrund
- This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.,CDC73,C1orf28,FIHP,HPTJT,HRPT1,HRPT2,HYX,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,CDC73
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Molekulargewicht
- 60 kDa
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Gen-ID
- 79577
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UniProt
- Q6P1J9
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
Target
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