ATP6V1E1 Antikörper (AA 77-226)

Produktnummer ABIN1678795

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ATP6V1E1 in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ATP6V1E1 Antikörper (AA 77-226) (ABIN1678795)

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ATP6V1E1 Antikörper

Bindungsspezifität: AA 77-226

Sequenz: NQARLKVLRA RDDLITDLLN EAKQRLSKVV KDTTRYQVLL DGLVLQGLYQ LLEPRMIVRC RKQDFPLVKA AVQKAIPMYK IATKNDVDVQ IDQESYLPED IAGGVEIYNG DRKIKVSNTL ESRLDLIAQQ MMPEVRGALF GANANRKFLD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1 (NP_001687.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ATP6V1E1

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Andere Bezeichnung: ATP6V1E1

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.,ATP6V1E1,ATP6E,ATP6E2,ATP6V1E,P31,Vma4,ARCL2C,Cancer,Signal Transduction,Endocrine & Metabolism,ATP6V1E1

Molekulargewicht: 22 kDa/23 kDa/26 kDa

Gen-ID: 529

UniProt: P36543

Pathways: Transition Metal Ion Homeostasis, Proton Transport