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ACTN2 Antikörper (AA 1-250)

Dieses Anti-ACTN2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACTN2 in WB, IHC und IF. Geeignet für Human.
Produktnummer ABIN1678557

Kurzübersicht für ACTN2 Antikörper (AA 1-250) (ABIN1678557)

Target

Alle ACTN2 Antikörper anzeigen
ACTN2 (Actinin, alpha 2 (ACTN2))

Reaktivität

  • 110
  • 65
  • 39
  • 8
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Human

Wirt

  • 80
  • 62
Kaninchen

Klonalität

  • 75
  • 67
Polyklonal

Konjugat

  • 61
  • 12
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ACTN2 Antikörper ist unkonjugiert

Applikation

  • 113
  • 82
  • 50
  • 19
  • 14
  • 13
  • 13
  • 13
  • 11
  • 10
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 57
    • 15
    • 9
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-250

    Sequenz

    MNQIEPGVQY NYVYDEDEYM IQEEEWDRDL LLDPAWEKQQ RKTFTAWCNS HLRKAGTQIE NIEEDFRNGL KLMLLLEVIS GERLPKPDRG KMRFHKIANV NKALDYIASK GVKLVSIGAE EIVDGNVKMT LGMIWTIILR FAIQDISVEE TSAKEGLLLW CQRKTAPYRN VNIQNFHTSW KDGLGLCALI HRHRPDLIDY SKLNKDDPIG NINLAMEIAE KHLDIPKMLD AEDIVNTPKP DERAIMTYVS

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ACTN2 (NP_001094.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    ACTN2 (Actinin, alpha 2 (ACTN2))

    Andere Bezeichnung

    ACTN2

    Hintergrund

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.,ACTN2,CMD1AA,CMH23,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Actins,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Cardiovascular,Heart,Contractility,Cardiac arrhythmias,ACTN2

    Molekulargewicht

    103 kDa

    Gen-ID

    88

    UniProt

    P35609

    Pathways

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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