HDAC2 Antikörper (C-Term)

Produktnummer ABIN1607886

Produktdetails anti-HDAC2 Antikörper

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross reactivity with HDAC2 from other sources has not been determined.

Reinheit: Anti-HDAC2 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC2. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat, and Primate based on 100 % sequence homology.

Endotoxin-Niveau: Low Endotoxin : No

Immunogen: HDAC2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminus region of human HDAC2.
Immunogen Type: Peptide

Anwendungsinformationen

Applikationshinweise: Anti-HDAC2 antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~59 kDa corresponding to the appropriate cell lysate or extract.
ELISA Dilution: 1:20.000 - 1:60.000
Immunohistochemistry Dilution: 1:100-1:500
IF Microscopy Dilution: 1:100-1:500
Western Blot Dilution: 1 µg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: Expiration date is six (6) months from date of opening.

Details zu HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Andere Bezeichnung: HDAC2 (HDAC2 Produkte)

Synonyme: HD2 antikoerper, RPD3 antikoerper, YAF1 antikoerper, D10Wsu179e antikoerper, Yy1bp antikoerper, mRPD3 antikoerper, HISTONE DEACETYLASE antikoerper, T1N24.9 antikoerper, T1N24_9 antikoerper, histone deacetylase 2 antikoerper, histone deacetylase 2 antikoerper, histone deacetylase 2 S homeolog antikoerper, HDAC2 antikoerper, Hdac2 antikoerper, hdac2.S antikoerper, HDA2 antikoerper

Hintergrund: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDAC2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human. Anti-HDAC2 antibodies are ideal for researchers interested in Breast Cancer, Cancer, Chromatin Research, Epigenetics, Histone Deacetylases, and Stem Cell Markers research. Synonyms: EC 3.5.1.98, HD2, histone deacetylase 2, RPD3, transcriptional regulator homolog RPD3, YAF1, YY1-associated factor 1

Gen-ID: 3066

NCBI Accession: NP_001518

UniProt: Q92769

Pathways: Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion