HDAC1 Antikörper (Internal Region)

Produktnummer ABIN1607883

Produktdetails anti-HDAC1 Antikörper

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross reactivity with HDAC1 from other sources has not been determined.

Reinheit: Anti-HDAC1 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC1. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat, and Primate based on 100 % sequence homology.

Endotoxin-Niveau: Low Endotoxin : No

Immunogen: HDAC1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human HDAC1.
Immunogen Type: Peptide

Anwendungsinformationen

Applikationshinweise: Anti-HDAC1 antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~62 kDa corresponding to the appropriate cell lysate or extract.
ELISA Dilution: 1:20.000 - 1:60.000
Immunohistochemistry Dilution: 1:100-1:500
IF Microscopy Dilution: 1:100-1:500
Western Blot Dilution: 1 µg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.59 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: Expiration date is six (6) months from date of opening.

Details zu HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Andere Bezeichnung: HDAC1 (HDAC1 Produkte)

Synonyme: GON-10 antikoerper, HD1 antikoerper, RPD3 antikoerper, RPD3L1 antikoerper, CG7471 antikoerper, DHDAC1 antikoerper, DRpd3 antikoerper, DmHDAC1 antikoerper, Dmel\\CG7471 antikoerper, E(var)3-64BC antikoerper, HDAC antikoerper, HDAC-1 antikoerper, HDAC1 antikoerper, Hdac1 antikoerper, Rpd3/HDAC antikoerper, Su(var)3-26 antikoerper, Su(var)326 antikoerper, Su(var)328 antikoerper, dHDAC-1 antikoerper, dHDAC1 antikoerper, dRPD3 antikoerper, dRpd3 antikoerper, dmHDA401 antikoerper, drpd3 antikoerper, hdac1 antikoerper, l(3)04556 antikoerper, l(3)64Cc antikoerper, rpd3 antikoerper, rpd[3] antikoerper, gon-10 antikoerper, hdac1b antikoerper, rpd3l1 antikoerper, Rpd3 antikoerper, GB14706 antikoerper, hdac1-b antikoerper, chunp6919 antikoerper, hdac-1 antikoerper, mp:zf637-2-001987 antikoerper, wu:fb19h11 antikoerper, wu:fi06f03 antikoerper, zgc:101582 antikoerper, zgc:65818 antikoerper, Hdac1-ps antikoerper, MommeD5 antikoerper, ARABIDOPSIS HISTONE DEACETYLASE 1 antikoerper, ARABIDOPSIS HISTONE DEACETYLASE 19 antikoerper, ATHD1 antikoerper, ATHDA19 antikoerper, ATRPD3A antikoerper, F20D10.250 antikoerper, F20D10_250 antikoerper, HDA1 antikoerper, HDA19 antikoerper, HISTONE DEACETYLASE antikoerper, HISTONE DEACETYLASE 19 antikoerper, HISTONE DEACETYLASE19 antikoerper, RPD3A antikoerper, histone deacetylase 1 antikoerper, HDM antikoerper, ab21 antikoerper, hdac1a antikoerper, histone deacetylase 1 antikoerper, Histone deacetylase 1 antikoerper, histone deacetylase antikoerper, histone deacetylase 1 S homeolog antikoerper, histone deacetylase Rpd3 antikoerper, histone deacetylase 1 L homeolog antikoerper, HDAC1 antikoerper, hdac1.S antikoerper, LOC411503 antikoerper, hdac1 antikoerper, Hdac1 antikoerper, HD1 antikoerper, hda-1 antikoerper, hdac1.L antikoerper, LOC748850 antikoerper

Hintergrund: HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Anti-HDAC1 antibodies are ideal for researchers interested in Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, Checkpoint signaling, Core ESC Like Genes, Chromatin Research, DNA Double Strand Break Repair, Epigenetics, DNA Repair, Histone Deacetylases, and Stem Cell Marker research. Synonyms: EC 3.5.1.98, GON-10, HD1DKFZp686H12203, histone deacetylase 1, reduced potassium dependency, yeast homolog-like 1, RPD3L1RPD3

Gen-ID: 3066

NCBI Accession: NP_001518

UniProt: Q92769

Pathways: Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis