ARHGAP22 Antikörper (pSer397)

Produktnummer ABIN1607879

Hersteller Produkt- Nr.: 600-401-j12

Der Kaninchen Polyklonal Anti-ARHGAP22-Antikörper wurde für WB, ELISA, IHC und FM validiert. Er ist geeignet, ARHGAP22 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ARHGAP22 Antikörper (pSer397) (ABIN1607879)

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Produktdetails anti-ARHGAP22 Antikörper

Bindungsspezifität: pSer397

Hersteller Produkt- Nr.: 600-401-j12

Hersteller: Rockland

Verwendungszweck: Arhgap22 phospho S397 Antibody

Kreuzreaktivität (Details): This antibody is specific for phosphorylated ARHGAP22 at Serine 397.

Produktmerkmale: Synonyms: rabbit anti-ARHGAP pS397 antibody, ARHGAP 22, ARHGAP-22, Rho-type GTPase-activating protein 22, RHOGAP2, Rho GTPase activating protein 22, rho GTPase-activating protein 22

Aufreinigung: Anti-ARHGAP22 pS397 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: ARHGAP22 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic phospho-peptide corresponding to the region surrounding mouse pS397 region of ARHGAP22.

Immunogen Type: Conjugated Peptide

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-ARHGAP22 pS397 antibody is tested for Western Blot and Immunostaining and useful for ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~77.8 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1:20,000 - 1:60,000

IF Microscopy Dilution: 1:100-1:500

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.07 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol with 1 mg/mL Bovine Serum Albumin (BSA)

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 6 months

Details zu ARHGAP22

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Andere Bezeichnung: Arhgap22

Hintergrund: Background: ARHGAP22 is a Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. It acts as a GTPase activator for RAC1 by converting it to an inactive GDP-bound state and also inhibits RAC1-dependent lamellipodia formation. It may also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter. Anti-ARHGAP22 [p Ser397] antibody is ideal for researchers interested in Diabetes Research, Lipid and Metabolism research.

Gen-ID: 239027

NCBI Accession: NP_722495

UniProt: Q8BL80