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ARHGAP22 Antikörper (pSer22)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARHGAP22 in WB, ELISA, IHC und FM. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Rockland
Produktnummer ABIN1607878
Hersteller Produkt- Nr.: 600-401-j11

Kurzübersicht für ARHGAP22 Antikörper (pSer22) (ABIN1607878)

Target

Alle ARHGAP22 Antikörper anzeigen
ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Reaktivität

Human, Maus, Ratte

Wirt

  • 16
Kaninchen

Klonalität

  • 16
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ARHGAP22 Antikörper ist unkonjugiert

Applikation

  • 16
  • 10
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
  • Bindungsspezifität

    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer22

    Hersteller Produkt- Nr.

    600-401-j11

    Hersteller

    Rockland

    Verwendungszweck

    Arhgap22 phospho S22 Antibody

    Kreuzreaktivität (Details)

    This antibody is specific for phosphorylated ARHGAP22 at Serine 22.

    Produktmerkmale

    Synonyms: rabbit anti-ARHGAP22 pS22 Antibody, Rho-type GTPase-activating protein 22, RHOGAP2, Rho GTPase activating protein 22, rho GTPase-activating protein 22, ARHGAP 22, ARHGAP-22

    Aufreinigung

    Anti-ARHGAP22 pS22 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: ARHGAP22 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic phospho-peptide corresponding to the region surrounding mouse pS22 region of ARHGAP22.

    Immunogen Type: Conjugated Peptide

  • Applikationshinweise

    Immunohistochemistry Dilution: 1:100-1:500

    Application Note: Anti-ARHGAP22 pS22 antibody is tested in Western Blot and ELISA useful for Immunostaining. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~77.8 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 1 μg/mL

    ELISA Dilution: 1:20,000 - 1:60,000

    IF Microscopy Dilution: 1:100-1:500

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.07 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: None

    Konservierungsmittel

    Without preservative

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    6 months
  • Target

    ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

    Andere Bezeichnung

    Arhgap22

    Hintergrund

    Background: ARHGAP22 is a Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. It acts as a GTPase activator for RAC1 by converting it to an inactive GDP-bound state and also inhibits RAC1-dependent lamellipodia formation. It may also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter. Anti-ARHGAP22 [p Ser22] antibody is ideal for researchers interested in Diabetes Research, Lipid and Metabolism research.

    Gen-ID

    239027

    NCBI Accession

    NP_722495

    UniProt

    Q8BL80
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