Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

KIF11 Antikörper

KIF11 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1607602
  • Target Alle KIF11 Antikörper anzeigen
    KIF11 (Kinesin Family Member 11 (KIF11))
    Reaktivität
    • 81
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 65
    • 16
    Kaninchen
    Klonalität
    • 55
    • 26
    Polyklonal
    Konjugat
    • 46
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIF11 Antikörper ist unkonjugiert
    Applikation
    • 68
    • 34
    • 19
    • 17
    • 16
    • 13
    • 13
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität (Details)
    Cross reactivity with Eg5 from other sources have not been determined.
    Reinheit
    Anti-Eg5 is directed against the human Eg5 protein. The product was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest reactivity with human.
    Endotoxin-Niveau
    Low Endotoxin : No
    Immunogen
    Eg5 was prepared from whole rabbit serum produced by repeated immunizations with a truncated Eg5 construct expressed in E. coli corresponding to human Eg5 protein.
    Immunogen Type: Recombinant Protein
    Top Product
    Discover our top product KIF11 Primärantikörper
  • Applikationshinweise
    Eg5 antibody has been tested for use in ELISA and western blot. For western blots expect a band of approximately 72 kDa in size corresponding to truncated kinesin-1 protein. Specific conditions for reactivity should be optimized by the end user.
    ELISA Dilution: 1:10.000
    Western Blot Dilution: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    46 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    Expiration date is one (1) year from date of opening.
  • Target
    KIF11 (Kinesin Family Member 11 (KIF11))
    Andere Bezeichnung
    Eg5 (KIF11 Produkte)
    Synonyme
    EG5 antikoerper, HKSP antikoerper, KNSL1 antikoerper, MCLMR antikoerper, TRIP5 antikoerper, Eg5 antikoerper, Kif8 antikoerper, Kifl1 antikoerper, Knsl1 antikoerper, F2H17.19 antikoerper, F2H17_19 antikoerper, DDBDRAFT_0189194 antikoerper, DDBDRAFT_0201556 antikoerper, DDB_0189194 antikoerper, DDB_0201556 antikoerper, XLEg5K1 antikoerper, XlEg5 antikoerper, cos2 antikoerper, costal2 antikoerper, eg5 antikoerper, hksp antikoerper, kif11 antikoerper, kif11-a antikoerper, kif11-b antikoerper, kif11b antikoerper, knsl1 antikoerper, trip5 antikoerper, Cos2 antikoerper, Costal2 antikoerper, XLEg5K2 antikoerper, kif11a antikoerper, kinesin family member 11 antikoerper, P-loop containing nucleoside triphosphate hydrolases superfamily protein antikoerper, kinesin family member 11 S homeolog antikoerper, kinesin family member 11 L homeolog antikoerper, KIF11 antikoerper, Kif11 antikoerper, AT2G36200 antikoerper, kif11 antikoerper, kif11.S antikoerper, kif11.L antikoerper
    Hintergrund
    Eg5 (also known as kinesin-5 and KIF11) is a homo-tetramer which cross-links anti-parallel microtubules in the mitotic spindle to maintain spindle bipolarity. Eg5, a member of the Kinesin-5 subclass of kinesins, is a plus-end-directed tetrameric kinesin-family protein that influences the assembly and organization of the mitotic spindle, a self-assembled and dynamic microtubule-based structure that orchestrates chromosome segregation in dividing cells. Eg5 action is essential: when it is depleted from the cytoplasm of meiotically-mature Xenopus laevis eggs, abnormal monopolar spindles form, preventing successful division. Eg5 is expressed in all cells during mitosis and in post-mitotic neurons during development. In developing neurons pharmacological inhibition and siRNA knockdown of Eg5 results in longer axons, more branches, fewer bouts of axon retraction and the inability of growth cones to turn on contact with repulsive substrates. In migratory neurons, inhibition of Eg5 causes neurons to migrate in a random pattern and form shorter leading processes. In adult neurons, Eg5 has a similar effect on inhibiting the rate of short microtubule transport so pharmacological inhibition of adult Eg5 (i.e Monastrol) may be a potential therapeutic tool for the augmentation of adult axon regeneration. Synonyms: Kinesin-5, KIF11
    Gen-ID
    3799
    NCBI Accession
    NP_004512
    UniProt
    P33176
Sie sind hier:
Kundenservice