BCAR1 Antikörper (Internal Region)

Produktnummer ABIN1590037

Dieser Ziege Polyklonal Antikörper detektiert spezifisch BCAR1 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für BCAR1 Antikörper (Internal Region) (ABIN1590037)

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser BCAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Güteklasse: Verified

Produktdetails anti-BCAR1 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: BCAR1

Sequenz: KQTSTFSKQT PHH

Spezifität: This antibody is expected to recognize reported isoforms1, 2, 3, 5, 6 and 7.

Kreuzreaktivität: Hund, Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: In paraffin embedded Human Uterus shows strong staining at the glandular side of the endometrial epithelium. Recommended concentration, 5-10 μg/mL.

Western Blot: Approx 100 kDa band observed in lysates of Human breast cancer and of cell line MCF7 (calculated MW of 97.9 kDa according to NP_001164185.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu BCAR1

Target: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Andere Bezeichnung: BCAR1

Hintergrund: BCAR1, breast cancer anti-estrogen resistance 1, CAS, CAS1, CASS1, CRKAS, P130Cas, Cas scaffolding protein family member 1, Crk-associated substrate p130Cas, breast cancer anti-estrogen resistance protein 1

Gen-ID: 9564, 12927, 25414

NCBI Accession: NP_001164185, NP_001164186, NP_001164187, NP_001164188, NP_001164189, NP_055382, NP_001164190, NP_001164191, NP_001164192

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling