BMP2 Antikörper
Kurzübersicht für BMP2 Antikörper (ABIN1589877)
Target
Alle BMP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- BMP-2 antibody
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Spezifität
- Recombinant human BMP-2
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Produktmerkmale
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Chromosomal location: 20p12
Anti-human BMP-2/4 polyclonal serum was produced from sera of rabbits pre- immunized with a highly purified synthetic peptide of the human BMP-2/4 sequence (C-terminal amino acids “C(SH)-L-D-E-Y-D-K-V-V-L-K-N-Y-Q-E-M-V-V-E-G“). -
Aufreinigung
- Anti-human BMP-2/4 polyclonal antiserum was purified by Protein A chromatography.
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Immunogen
- Recombinant human BMP-2
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Isotyp
- IgG
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Applikationshinweise
- Western Blot: Use 2-5 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS
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Handhabung
- Centrifuge vial prior to opening.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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Haltbarkeit
- 24 months
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- BMP2 (Bone Morphogenetic Protein 2 (BMP2))
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Andere Bezeichnung
- BMP-2
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Hintergrund
- Bone morphogenetic protein 2, BDA2, BMP2A, bone morphogenetic protein 4, ZYME, BMP2B, OFC11, BMP2B1, MCOPS6,Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector. The antibody cross-reacts displays cross-reaction with human BMP-4 monomers in Western Blot.
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Gen-ID
- 650
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NCBI Accession
- NM_001200, NP_001191
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UniProt
- P12643
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation
Target
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