EMILIN2 Antikörper

Produktnummer ABIN1589876

Der Maus Monoklonal anti-EMILIN2 Antikörper wird verwendet zum Nachweis von EMILIN2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für EMILIN2 Antikörper (ABIN1589876)

Target: EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EMILIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 828B3B3

Produktdetails anti-EMILIN2 Antikörper

Verwendungszweck: Emilin-2 antibody

Spezifität: Recombinant gC1q domain of EMILIN2

Produktmerkmale: Chromosomal location: 18p11.3

Aufreinigung: The IgG2b/kappa fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 μm filtered solution in phosphate-buffered saline (PBS).

Immunogen: Recombinant gC1q domain of EMILIN2

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Western Blot: Use 2-5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handhabung: Centrifuge vial prior to opening.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Haltbarkeit: 24 months

Details zu EMILIN2

Target: EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))

Andere Bezeichnung: Emilin-2

Hintergrund: EMILIN2, FOAP-10, EMILIN-2,Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.

Gen-ID: 84034

NCBI Accession: NM_032048, NP_114437

UniProt: Q9BXX0