Peripherin Antikörper

Produktnummer ABIN1580456

Produktdetails anti-Peripherin Antikörper

Target: Peripherin (PRPH)

Reaktivität: Säugetier

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Peripherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Aufreinigung: conc. tissue culture supernatant

Klon: 7C5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: MCA-7C5 is supplied as 500 µLs of concentrated tissue culture supernatant. For immunocytochemistry we recommend dilutions of 1:200, and for western blot 1:1,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4°C. For safest long-term storage, maintain aliquots at -80°C or -20°C. Avoid repeated freeze-thaw cycles.

Details zu Peripherin

Target: Peripherin (PRPH)

Andere Bezeichnung: Peripherin (PRPH Produkte)

Synonyme: NEF4 antikoerper, PRPH1 antikoerper, Prph1 antikoerper, Perf antikoerper, nef4 antikoerper, prph1 antikoerper, MGC69454 antikoerper, if3 antikoerper, plasticin antikoerper, zgc:111926 antikoerper, peripherin antikoerper, peripherin L homeolog antikoerper, PRPH antikoerper, Prph antikoerper, prph antikoerper, prph.L antikoerper

Hintergrund: Peripherin is a approx. 57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. The HGNC name for this protein is PRPH. Subsequently peripherin was found in some sensory and other neurons of the central nervous system and also in rat pheochromacytoma PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. The characterization of an antibody very similar to MCA-7C5 has been published. The HGNC name for this protein is PRPH.