Fc epsilon RI/FCER1A Antikörper
Kurzübersicht für Fc epsilon RI/FCER1A Antikörper (ABIN1558260)
Target
Alle Fc epsilon RI/FCER1A (FCER1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- The antibody recognizes an epitope within the a2 domain of the human high affinity IgE receptor (FceRIa). It inhibits binding of IgE to this receptor and is suitable to detect receptors expressed on primary cells and cell lines (e.g mast cells and basophils). It can also be used as weak to moderate cross-linking agent for IgE-independent triggering of effector cells and to detect FceRIa in ELISA and W-blots.
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Aufreinigung
- Affinity - purified from cell culture supernatant by Immunoaffinity Chromatography on anti-mouse IgG1 agarose
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Reinheit
- 98 % (Gel Permeation Chromatography)
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Sterilität
- Sterile filtered
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Immunogen
- Recombinant human FCER1A
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Can be used for functional mast cell / basophil assays
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH=7.2, sterile filtered, contains no NaN3
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Konservierungsmittel
- Azide free
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Handhabung
- Handle under sterile conditions, the mAb is formulated in sterile buffer solution and does not contain sodium azide as preservative.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8°C. For long term storage, aliquot and store at -20°C or -80°C
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Andere Bezeichnung
- FCER1A
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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