HMOX2 Antikörper

Produktnummer ABIN155125

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HMOX2 in WB, IP und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Affe und Hamster.

Kurzübersicht für HMOX2 Antikörper (ABIN155125)

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reaktivität: Human, Maus, Ratte, Affe, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HMOX2 Antikörper

Spezifität: The antibody recognizes ~36 kDa Heme-Oxygenase-2.

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide surrounding amino acid 25 of human HO-2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry on frozen sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Andere Bezeichnung: Heme Oxygenase 2 (HMOX2)

Hintergrund: Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two heme oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. At the amino acid level, HO-1 and HO-2 are 42 % homologous. However, each isozyme is evolutionary highly conserved. HO-1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO-1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO-2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO-2 is the most prevalent form in most tissues, except the spleen where HO-1 levels are predominant under normal conditions.Synonyms: HO-2, HO2

Gen-ID: 3163

NCBI Accession: NP_001120676

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis