HMOX2 Antikörper

Produktnummer ABIN155125

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HMOX2 in WB, IP und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Affe und Hamster.

Kurzübersicht für HMOX2 Antikörper (ABIN155125)

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reaktivität: Human, Maus, Ratte, Affe, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HMOX2 Antikörper

Spezifität: The antibody recognizes ~36 kDa Heme-Oxygenase-2.

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide surrounding amino acid 25 of human HO-2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry on frozen sections: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Andere Bezeichnung: Heme Oxygenase 2 (HMOX2)

Hintergrund: Heme oxygenase (HO) is a microsomal enzyme that oxidatively cleaves heme, a pro-oxidant, into carbon monoxide and biliverdin. Two heme oxygenase isozymes, termed HO-1 and HO-2, have been identified so far. At the amino acid level, HO-1 and HO-2 are 42 % homologous. However, each isozyme is evolutionary highly conserved. HO-1 is the inducible form of the enzyme and is therefore also referred to as stress protein Hsp32. Expression of HO-1 can be induced by a variety of stimuli such as heme, metals, hormones, UV radiation and sulfhydryl depleting agents. In contrast, HO-2 is the constituitive form of the enzyme. It is not inducible by exogeneous stimuli and HO-2 is the most prevalent form in most tissues, except the spleen where HO-1 levels are predominant under normal conditions.Synonyms: HO-2, HO2

Gen-ID: 3163

NCBI Accession: NP_001120676

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis