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MBP Antikörper

Der Maus Monoklonal Anti-MBP-Antikörper wurde für WB und IF validiert. Er ist geeignet, MBP in Proben von Human zu detektieren.
Produktnummer ABIN1539854

Kurzübersicht für MBP Antikörper (ABIN1539854)

Target

MBP

Reaktivität

  • 86
  • 50
  • 46
  • 4
  • 2
  • 2
Human

Wirt

  • 74
  • 22
  • 3
  • 1
Maus

Klonalität

  • 71
  • 29
Monoklonal

Konjugat

  • 58
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser MBP Antikörper ist unkonjugiert

Applikation

  • 70
  • 35
  • 35
  • 31
  • 29
  • 26
  • 26
  • 24
  • 10
  • 8
  • 8
  • 7
  • 6
  • 1
Western Blotting (WB), Immunofluorescence (IF)

Klon

408CT17-4-3
  • Aufreinigung

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    Immunogen

    Purified His-tagged MBP protein(Fragment) was used to produced this monoclonal antibody.

    Isotyp

    IgM
  • Applikationshinweise

    IF: 1:10~50. WB: 1:5000~16000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    MBP Antibody (Ascites) can be refrigerated at 2-8Â °C for up to 6 months. For long term storage, keep at -20Â °C.

    Haltbarkeit

    6 months
  • Target

    MBP

    Hintergrund

    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq].

    Molekulargewicht

    33117

    Gen-ID

    4155

    NCBI Accession

    NP_001020252, NP_001020261, NP_001020263, NP_001020271, NP_001020272, NP_002376

    UniProt

    P02686
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