Dieses Anti-Myosin 9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Myosin 9 in DB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MYH9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y158 of human MYH9.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Phospho-MYH9-Y158 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-MYH9-Y158 Antibody at -20 °C.
Haltbarkeit
6 months
Almeida, Mesquita, Cruz, Osório, Custódio, Brito, Vingadassalom, Martins, Leong, Holden, Cabanes, Sousa: "Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8383-95, (2015) (PubMed).
Target
Myosin 9 (MYH9)
Andere Bezeichnung
MYH9
Hintergrund
This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.