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Myosin 9 Antikörper (pTyr158)

Dieses Anti-Myosin 9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Myosin 9 in DB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN1539741

Kurzübersicht für Myosin 9 Antikörper (pTyr158) (ABIN1539741)

Target

Alle Myosin 9 (MYH9) Antikörper anzeigen
Myosin 9 (MYH9)

Reaktivität

  • 66
  • 14
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 52
  • 12
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 52
  • 16
Polyklonal

Konjugat

  • 42
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Myosin 9 Antikörper ist unkonjugiert

Applikation

  • 48
  • 38
  • 19
  • 14
  • 11
  • 10
  • 8
  • 8
  • 2
  • 2
  • 1
  • 1
Dot Blot (DB)

Klon

RB36361
  • Bindungsspezifität

    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr158

    Homologie

    C, M, Rat

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This MYH9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y158 of human MYH9.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    DB: 1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Phospho-MYH9-Y158 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-MYH9-Y158 Antibody at -20 °C.

    Haltbarkeit

    6 months
  • Almeida, Mesquita, Cruz, Osório, Custódio, Brito, Vingadassalom, Martins, Leong, Holden, Cabanes, Sousa: "Src-dependent tyrosine phosphorylation of non-muscle myosin heavy chain-IIA restricts Listeria monocytogenes cellular infection." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8383-95, (2015) (PubMed).

  • Target

    Myosin 9 (MYH9)

    Andere Bezeichnung

    MYH9

    Hintergrund

    This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

    Molekulargewicht

    226532

    Gen-ID

    4627

    NCBI Accession

    NP_002464

    UniProt

    P35579

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex
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