SAFB Antikörper (N-Term)

Produktnummer ABIN1539521

Der Kaninchen Polyklonal Anti-SAFB-Antikörper wurde für WB validiert. Er ist geeignet, SAFB in Proben von Human zu detektieren.

Kurzübersicht für SAFB Antikörper (N-Term) (ABIN1539521)

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37542

Produktdetails anti-SAFB Antikörper

Bindungsspezifität: AA 65-94, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SAFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human SAFB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SAFB Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu SAFB

Target: SAFB (Scaffold Attachment Factor B (SAFB))

Andere Bezeichnung: SAFB

Hintergrund: This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.

Molekulargewicht: 102642

Gen-ID: 6294

NCBI Accession: NP_001188267, NP_001188268, NP_001188269, NP_002958

UniProt: Q15424

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway