SPRY2 Antikörper (N-Term)

Produktnummer ABIN1539429

Dieses Anti-SPRY2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPRY2 in WB. Geeignet für Human und Maus.

Kurzübersicht für SPRY2 Antikörper (N-Term) (ABIN1539429)

Target: SPRY2 (Sprouty Homolog 2 (SPRY2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB36778

Produktdetails anti-SPRY2 Antikörper

Bindungsspezifität: AA 6-35, N-Term

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPRY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human SPRY2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SPRY2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu SPRY2

Target: SPRY2 (Sprouty Homolog 2 (SPRY2))

Andere Bezeichnung: SPRY2

Hintergrund: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq].

Molekulargewicht: 34688

Gen-ID: 10253

NCBI Accession: NP_005833

UniProt: O43597

Pathways: EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation