Bestrophin 3 Antikörper (N-Term)

Produktnummer ABIN1539351

Dieses Anti-Bestrophin 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Bestrophin 3 in WB. Geeignet für Human.

Kurzübersicht für Bestrophin 3 Antikörper (N-Term) (ABIN1539351)

Target: Bestrophin 3 (BEST3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39849

Produktdetails anti-Bestrophin 3 Antikörper

Bindungsspezifität: AA 40-68, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: BEST3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Bestrophin 3

Target: Bestrophin 3 (BEST3)

Andere Bezeichnung: BEST3

Hintergrund: BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738], Tsunenari et al., 2003 [PubMed 12907679]).

Molekulargewicht: 76107

Gen-ID: 144453

NCBI Accession: NP_116124, NP_689652

UniProt: Q8N1M1