ITM2C Antikörper (N-Term)
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- Target Alle ITM2C Antikörper anzeigen
- ITM2C (Integral Membrane Protein 2C (ITM2C))
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Bindungsspezifität
- AA 27-55, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ITM2C Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- Pr
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This ITM2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.
- Klon
- RB36714
- Isotyp
- Ig Fraction
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anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibody
ITM2C Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf, Fledermaus, Affe, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- ITM2C Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- ITM2C (Integral Membrane Protein 2C (ITM2C))
- Andere Bezeichnung
- ITM2C (ITM2C Produkte)
- Synonyme
- 3110038L02Rik antikoerper, BRI3 antikoerper, Bricd2c antikoerper, E25 antikoerper, E25C antikoerper, ITM3 antikoerper, BRICD2C antikoerper, fj35c02 antikoerper, itm2c antikoerper, wu:fj35c02 antikoerper, zgc:66349 antikoerper, wu:fj52a04 antikoerper, zgc:92783 antikoerper, integral membrane protein 2C antikoerper, integral membrane protein 2Cb antikoerper, integral membrane protein 2Ca antikoerper, Itm2c antikoerper, ITM2C antikoerper, itm2cb antikoerper, itm2ca antikoerper
- Hintergrund
- Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
- Molekulargewicht
- 30224
- Gen-ID
- 81618
- NCBI Accession
- NP_001012532, NP_001012534, NP_112188
- UniProt
- Q9NQX7
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