DDX21 Antikörper (N-Term)

Produktnummer ABIN1539008

Der Kaninchen Polyklonal Anti-DDX21-Antikörper wurde für WB validiert. Er ist geeignet, DDX21 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für DDX21 Antikörper (N-Term) (ABIN1539008)

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37016

Produktdetails anti-DDX21 Antikörper

Bindungsspezifität: AA 128-156, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DDX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DDX21 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-DDX21 Antikörper (ABIN1539008)

Smith, Krumpelbeck, Jegga, Prell, Matrka, Kappes, Greis, Ali, Meetei, Wells: "The nuclear DEK interactome supports multi-functionality." in: Proteins, Vol. 86, Issue 1, pp. 88-97, (2018) (PubMed).

Details zu DDX21

Target: DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

Andere Bezeichnung: DDX21

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

Molekulargewicht: 87344

Gen-ID: 9188

NCBI Accession: NP_001243839, NP_004719

UniProt: Q9NR30

Pathways: SARS-CoV-2 Protein Interaktom