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DMPK Antikörper (N-Term)

DMPK Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36813 unconjugated
Produktnummer ABIN1538919
  • Target Alle DMPK Antikörper anzeigen
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-39, N-Term
    Reaktivität
    • 41
    • 21
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 53
    • 5
    Kaninchen
    Klonalität
    • 55
    • 3
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DMPK Antikörper ist unkonjugiert
    Applikation
    • 31
    • 24
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This DMPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human DMPK.
    Klon
    RB36813
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    DMPK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    Andere Bezeichnung
    DMPK (DMPK Produkte)
    Synonyme
    DMPK antikoerper, DM antikoerper, DM1 antikoerper, DM1PK antikoerper, DMK antikoerper, MDPK antikoerper, MT-PK antikoerper, Dm15 antikoerper, DM1 protein kinase antikoerper, dystrophia myotonica-protein kinase antikoerper, DMPK antikoerper, Dmpk antikoerper
    Hintergrund
    The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Molekulargewicht
    69385
    Gen-ID
    1760
    NCBI Accession
    NP_001075029, NP_001075031, NP_001075032, NP_004400
    UniProt
    Q09013
    Pathways
    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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