Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DMPK Antikörper (N-Term)

Dieses Anti-DMPK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DMPK in WB. Geeignet für Human.
Produktnummer ABIN1538919

Kurzübersicht für DMPK Antikörper (N-Term) (ABIN1538919)

Target

Alle DMPK Antikörper anzeigen
DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Reaktivität

  • 38
  • 22
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 53
  • 5
Kaninchen

Klonalität

  • 55
  • 3
Polyklonal

Konjugat

  • 28
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DMPK Antikörper ist unkonjugiert

Applikation

  • 31
  • 21
  • 13
  • 13
  • 10
  • 8
  • 7
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB)

Klon

RB36813
  • Bindungsspezifität

    • 15
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-39, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This DMPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human DMPK.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    DMPK Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    Haltbarkeit

    6 months
  • Target

    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

    Andere Bezeichnung

    DMPK

    Hintergrund

    The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

    Molekulargewicht

    69385

    Gen-ID

    1760

    NCBI Accession

    NP_001075029, NP_001075031, NP_001075032, NP_004400

    UniProt

    Q09013

    Pathways

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
Sie sind hier:
Chat with us!