THOC6 Antikörper (AA 96-123)

Produktnummer ABIN1538708

Der Kaninchen Polyklonal Anti-THOC6-Antikörper wurde für WB validiert. Er ist geeignet, THOC6 in Proben von Human und Maus zu detektieren.

Kurzübersicht für THOC6 Antikörper (AA 96-123) (ABIN1538708)

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THOC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB38031

Produktdetails anti-THOC6 Antikörper

Bindungsspezifität: AA 96-123

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This THOC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human THOC6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: THOC6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu THOC6

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Andere Bezeichnung: THOC6

Hintergrund: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.

Molekulargewicht: 37535

Gen-ID: 79228

NCBI Accession: NP_001135822, NP_077315

UniProt: Q86W42