MECOM Antikörper (AA 81-109)

Produktnummer ABIN1538639

Der Kaninchen Polyklonal Anti-MECOM-Antikörper wurde für WB validiert. Er ist geeignet, MECOM in Proben von Maus zu detektieren.

Kurzübersicht für MECOM Antikörper (AA 81-109) (ABIN1538639)

Target: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MECOM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB34340

Produktdetails anti-MECOM Antikörper

Bindungsspezifität: AA 81-109

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the Central region of human MDS1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: MDS1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu MECOM

Target: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Andere Bezeichnung: MDS1

Hintergrund: MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.

Gen-ID: 2122

NCBI Accession: NP_004982

UniProt: Q13465