LILRB1 Antikörper (AA 345-374)

Produktnummer ABIN1538335

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LILRB1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LILRB1 Antikörper (AA 345-374) (ABIN1538335)

Target: LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB36844

Produktdetails anti-LILRB1 Antikörper

Bindungsspezifität: AA 345-374

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LILRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the Central region of human LILRB1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: LILRB1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu LILRB1

Target: LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))

Andere Bezeichnung: LILRB1

Hintergrund: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 70819

Gen-ID: 10859

NCBI Accession: NP_001075106, NP_001075107, NP_001075108, NP_001265327, NP_001265328, NP_006660

UniProt: Q8NHL6

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response