PCDHA1 Antikörper (AA 288-316)

Produktnummer ABIN1538249

Der Kaninchen Polyklonal anti-PCDHA1 Antikörper wird verwendet zum Nachweis von PCDHA1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für PCDHA1 Antikörper (AA 288-316) (ABIN1538249)

Target: PCDHA1 (Protocadherin alpha 1 (PCDHA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB32960

Produktdetails anti-PCDHA1 Antikörper

Bindungsspezifität: AA 288-316

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PCDHA1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PCDHA1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PCDHA1

Target: PCDHA1 (Protocadherin alpha 1 (PCDHA1))

Andere Bezeichnung: PCDHA1

Hintergrund: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molekulargewicht: 102952

Gen-ID: 56147

NCBI Accession: NP_061723, NP_113598, NP_113599

UniProt: Q9Y5I3