This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PPIL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-153 amino acids from the Central region of human PPIL5.
LRR1
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
PPIL5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Haltbarkeit
6 months
Target
PPIL5 (LRR1)
(Leucine Rich Repeat Protein 1 (LRR1))
Andere Bezeichnung
PPIL5
Hintergrund
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.