Catalase Antikörper (AA 152-180)

Produktnummer ABIN1537700

Der Maus Monoklonal Anti-Catalase-Antikörper wurde für WB validiert. Er ist geeignet, Catalase in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Catalase Antikörper (AA 152-180) (ABIN1537700)

Target: Catalase (CAT)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Catalase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 626CT4-3-8

Produktdetails anti-Catalase Antikörper

Bindungsspezifität: AA 152-180

Homologie: B, Zf, Pig, Rat

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CAT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CAT.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:1600. WB: 1:1600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CAT Antibody (Center)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-Catalase Antikörper (ABIN1537700)

Pereira, Igea, Canovas, Dolado, Nebreda: "Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK." in: EMBO molecular medicine, Vol. 5, Issue 11, pp. 1759-74, (2013) (PubMed).

Details zu Catalase

Target: Catalase (CAT)

Andere Bezeichnung: CAT

Hintergrund: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Molekulargewicht: 59756

Gen-ID: 847

NCBI Accession: NP_001743

UniProt: P04040

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism