This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3.
DSC3
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
DSC3 Antibody (C-term) can be refrigerated at 2-8Â °C for up to 6 months. For long term storage, keep at -20Â °C.
Haltbarkeit
6 months
Target
Desmocollin 3 (DSC3)
Andere Bezeichnung
DSC3
Hintergrund
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.