TLK1 Antikörper (C-Term)

Produktnummer ABIN1537558

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLK1 in WB. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für TLK1 Antikörper (C-Term) (ABIN1537558)

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37154

Produktdetails anti-TLK1 Antikörper

Bindungsspezifität: AA 701-728, C-Term

Homologie: H

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Mouse Tlk1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Andere Bezeichnung: Tlk1

Hintergrund: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity). Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity).

Molekulargewicht: 86624

Gen-ID: 228012

NCBI Accession: NP_766252

UniProt: Q8C0V0