Apoptosis Inhibitor 5 Antikörper (C-Term)

Produktnummer ABIN1537392

Dieses Anti-Apoptosis Inhibitor 5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Apoptosis Inhibitor 5 in WB. Geeignet für Human.

Kurzübersicht für Apoptosis Inhibitor 5 Antikörper (C-Term) (ABIN1537392)

Target: Apoptosis Inhibitor 5 (API5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apoptosis Inhibitor 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39469

Produktdetails anti-Apoptosis Inhibitor 5 Antikörper

Bindungsspezifität: AA 482-510, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This API5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-510 amino acids from the C-terminal region of human API5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: API5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Andere Bezeichnung: API5

Hintergrund: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

Molekulargewicht: 59005

Gen-ID: 8539

NCBI Accession: NP_001136402, NP_001136403, NP_001230676, NP_006586

UniProt: Q9BZZ5

Pathways: Growth Factor Binding