GPR39 Antikörper (C-Term)

Produktnummer ABIN1537229

Der Kaninchen Polyklonal Anti-GPR39-Antikörper wurde für WB validiert. Er ist geeignet, GPR39 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für GPR39 Antikörper (C-Term) (ABIN1537229)

Target: GPR39 (G Protein-Coupled Receptor 39 (GPR39))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR39 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40394

Produktdetails anti-GPR39 Antikörper

Bindungsspezifität: AA 379-407, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GPR39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-407 amino acids from the C-terminal region of human GPR39.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: GPR39 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-GPR39 Antikörper (ABIN1537229)

Kolodziejski, Pruszynska-Oszmalek, Sassek, Kaczmarek, Szczepankiewicz, Billert, Mackowiak, Strowski, Nowak: "Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes." in: Journal of diabetes, Vol. 9, Issue 4, pp. 353-361, (2017) (PubMed).

Details zu GPR39

Target: GPR39 (G Protein-Coupled Receptor 39 (GPR39))

Andere Bezeichnung: GPR39

Hintergrund: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).

Molekulargewicht: 51329

Gen-ID: 2863

NCBI Accession: NP_001499

UniProt: O43194

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour