This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
OSTM1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Haltbarkeit
6 months
Target
OSTM1
(Osteopetrosis Associated Transmembrane Protein 1 (OSTM1))
Andere Bezeichnung
OSTM1
Hintergrund
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.