LIN7A Antikörper (C-Term)

Produktnummer ABIN1536800

Der Kaninchen Polyklonal Anti-LIN7A-Antikörper wurde für WB validiert. Er ist geeignet, LIN7A in Proben von Human zu detektieren.

Kurzübersicht für LIN7A Antikörper (C-Term) (ABIN1536800)

Target: LIN7A (Lin-7 Homolog A (LIN7A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIN7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37057

Produktdetails anti-LIN7A Antikörper

Bindungsspezifität: AA 180-207, C-Term

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LIN7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-207 amino acids from the C-terminal region of human LIN7A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: LIN7A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu LIN7A

Target: LIN7A (Lin-7 Homolog A (LIN7A))

Andere Bezeichnung: LIN7A

Hintergrund: LIN7A plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Molekulargewicht: 25997

Gen-ID: 8825

NCBI Accession: NP_004655

UniProt: O14910

Pathways: Synaptic Membrane