ITGA7 Antikörper (Cleaved-Glu959)
Kurzübersicht für ITGA7 Antikörper (Cleaved-Glu959) (ABIN1536135)
Target
Alle ITGA7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 940-989, Cleaved-Glu959
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Verwendungszweck
- Cleaved-Integrin α7 LC (E959) Antibody
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Spezifität
- Cleaved-Integrin α7 LC (E959) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α7 LC protein resulting from cleavage adjacent to E959.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human ITGA7. AA range:940-989
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- ITGA7 (Integrin, alpha 7 (ITGA7))
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Andere Bezeichnung
- ITGA7
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Hintergrund
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Synonyms: ITGA7, Integrin alpha-7
Background: integrin subunit alpha 7(ITGA7) Homo sapiens The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009],
Gene Name: ITGA7
Protein Name: Integrin alpha-7
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Molekulargewicht
- 25 kDa
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Gen-ID
- 3679
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OMIM
- 600536
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UniProt
- Q13683
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Pathways
- Integrin Complex
Target
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