Cathepsin L2 Antikörper (Cleaved-Leu114)
Kurzübersicht für Cathepsin L2 Antikörper (Cleaved-Leu114) (ABIN1536113)
Target
Alle Cathepsin L2 (CTSL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 95-144, Cleaved-Leu114
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Verwendungszweck
- Cleaved-Cathepsin L2 (L114) Antibody
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Spezifität
- Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human CATL2. AA range:95-144
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Cathepsin L2 (CTSL2)
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Andere Bezeichnung
- CATL2
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Hintergrund
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Synonyms: CTSL2, CATL2, CTSU, CTSV, Cathepsin L2, Cathepsin U, Cathepsin V
Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011],
Gene Name: CTSL2
Protein Name: Cathepsin L2
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Molekulargewicht
- 37 kDa
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Gen-ID
- 1515
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OMIM
- 603308
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UniProt
- O60911
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Pathways
- Toll-Like Receptors Cascades
Target
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