CPT1C Antikörper (Cleaved-Thr288)

Produktnummer ABIN1536112

Der Kaninchen Polyklonal anti-CPT1C Antikörper wird verwendet zum Nachweis von CPT1C in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für CPT1C Antikörper (Cleaved-Thr288) (ABIN1536112)

Target: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CPT1C Antikörper

Bindungsspezifität: AA 239-288, Cleaved-Thr288

Verwendungszweck: Cleaved-Cathepsin L1 HC (T288) Antibody

Spezifität: Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L1 HC protein resulting from cleavage adjacent to T288.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CATL1. AA range:239-288

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CPT1C

Target: CPT1C (Carnitine Palmitoyltransferase 1C (Brain) (CPT1C))

Andere Bezeichnung: CATL1

Hintergrund:

Synonyms: CTSL1, CTSL, Cathepsin L1, Major excreted protein, MEP

Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],

Gene Name: CTSL1

Protein Name: Cathepsin L1

Molekulargewicht: 30 kDa

Gen-ID: 1514

OMIM: 116880

UniProt: P07711

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process