AVPR1B Antikörper (AA 275-324)

Produktnummer ABIN1536013

Der Kaninchen Polyklonal anti-AVPR1B Antikörper wird verwendet zum Nachweis von AVPR1B in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für AVPR1B Antikörper (AA 275-324) (ABIN1536013)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AVPR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-AVPR1B Antikörper

Bindungsspezifität: AA 275-324

Verwendungszweck: AVP Receptor V3 Antibody

Spezifität: AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Andere Bezeichnung: AVPR1B

Hintergrund:

Synonyms: AVPR1B, AVPR3, VPR3, Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],

Gene Name: AVPR1B

Protein Name: Vasopressin V1b receptor

Molekulargewicht: 46 kDa

Gen-ID: 553

OMIM: 600264

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones